Case studies

#CASE-STUDY 01

Reduction of HbA1c

Goal

To discover and characterise a natural peptide network that reduces HbA1c

Targets

HbA1C (glycated haemoglobin) develops when haemoglobin, a protein within red blood cells that carries oxygen throughout your body, joins with glucose in the blood, becoming ‘glycated’. HbA1c levels give overall picture of average blood sugar levels have been over a period of weeks/months. The higher the HbA1c, the greater the risk of developing diabetes or diabetes related complications

Results

Our peptide showed significant upregulation of glucose uptake in skeletal muscle in-vitro as well as in-vivo models, and a significant reduction of HbA1c in randomized double blind human clinical study

* denotes significance vs Placebo

Data from double-blind, placebo-controlled clinical study involving 77 participants.  Manuscript in preparation for submission.

Discovered by AI

Clinically Proven

Patented

Food grade

Non GMO

Plant based

#CASE-STUDY 02

Benefits for the Skin

Goal

To develop a new, natural, food derived peptide network with multiple applications in the body care arena

Targets

Hair care, to help manage dandruff and scalp inflammation and body care, to help manage sore and inflamed skin

Results

Anti-inflammatory peptide discovered from rice.

Clinical Study 1, Leave On Body Lotion, Legs

1 Week of Application: Moisturization increased by 33%

1 Month of Application: 92% participants stated their skin felt soothed, smooth & nourished

Clinical Study 2, Leave On Body Lotion, Belly

1 Month of Application: Skin firmness increased by 27%. 79% participants stated their skin was more supple, 82% reported increased comfort in skin

Clinical Study 3, Wash Out Shampoo, Hair

3 Weeks of Application 3 x per Week: Scalp redness decreased by 9%. pH level of scalp was 0.4units lower (difference between sensitive and normal scalp)

Before use of Peptide

Drag green line to see before and after

After use of Peptide for 28 days

Discovered by AI

Clinically Proven

Patented

Food grade

Non GMO

Plant based

Novel

Characterised

#CASE-STUDY 03

Anti-Inflammatory for animal use

Goal

To develop a bioactive peptide solution from a food material to specifically target growth in animals.

Targets

TNF-α – a potent pro-inflammatory cytokine involved in early inflammatory events

IL-6 – a protein which helps regulate immune responses

Results

  • Decreases LPS-induced TNF-α levels by up to 75%
  • Decreases LPS-induced IL-6 levels by up to 65%
  • Tested in Ex-vivo moving to in-vivo

Reduction in TNF-α

Reduction in IL-6

Discovered by AI

Bioavailable

Patentable

Food grade

Non GMO

Plant based

Novel

#CASE-STUDY 04

IL17 reduction

Goal

To discover and characterise a natural peptide network that modulates IL-17A signalling and can thus be used in the management of certain increasingly common conditions.

Targets

IL17 – a pro-inflammatory cytokine with important roles in defence against bacteria and fungi. However, when chronically activated, it can lead to the development of inflammatory conditions of the skin, joints, respiratory and immune systems

Results

Our peptide showed significant inhibition of IL17 across several doses inclusion levels versus control, demonstrating a reduction in cytokines and alleviating chronic inflammation

Discovered by AI

Novel

Patentable

Food grade

Non GMO

Plant based

Bioavailable

#CASE-STUDY 05

Cellular Aging in double-blind placebo

Goal

To discover and characterise a naturally inspired peptide that addresses key areas of skin health:  wrinkles and aging

Targets

Extracellular matrix proteins, collagen and elastin, critical for skin integrity (firmness, wrinkles) and skin inflammation were targeted with this peptide

Results

  • Decreases LPS-induced TNF-α levels by up to 75%
  • Decreases LPS-induced IL-6 levels by up to 65%
  • Tested in Ex-vivo moving to in-vivo

Primos 3D Light Scan. Blue represents wrinkle depth.
N=20 placebo; N=20 treatment

Before use of Peptide

Drag green line to see before and after

After use of Peptide for 28 days
Before use of Peptide

Drag green line to see before and after

After use of Peptide for 28 days

International Journal of Cosmetic Science
“The anti-ageing effects of a natural peptide discovered by Artificial Intelligence”  
To read the paper visit: https://onlinelibrary.wiley.com/doi/10.1111/ics.12635

Discovered by AI

Clinically Proven

Patented

Plant inspired